March 06, 2023 Written by Dr. Thomas Wnorowski

Your Gut+ and Butyrate Start Guide: Timing, Dosage, Probiotics, and More

Key Points:

  • BodyBio Gut+ and Butyrate are two of our most powerful supplements for gut dysbiosis and microbiome support. Here, we break down the differences between the two supplements and which one you should take.

  • Some people can replace their everyday butyrate supplement with Gut+ (since Gut+ includes tributyrin, a highly absorbable form of butyrate.) However, this really depends on your current gut health status and goals. It’s perfectly acceptable and safe to take both supplements at the same time, too.

  • While probiotics can be helpful for the body, they don’t usually address the root cause of gut health issues. And, if not supported with prebiotics and postbiotics, they can die off before doing any good in your gut ecosystem. That’s why we focus on strengthening your gut with prebiotics and postbiotics, so your microbiome can develop on its own.


Congratulations! You’ve taken the first step toward gut-brain axis support, improved immune system function, and the healthiest BM’s of your life. 

Gut+ is the do-it-all gut health supplement that combines prebiotics and postbiotics to support your natural microbiome, regulate motility, and reduce uncomfortable gut symptoms like gas and bloating.*

But how do you get started taking our newest gut health champion? Here, we’ll cover all of your frequently asked questions regarding Gut+, digestive health, and how this new and advanced supplement interacts with Butyrate.

Table of Contents:

So I Just Received Gut+ — Now What?

First, take a deep breath. Your gut symptoms aren’t forever — and Gut+ is bringing you one step closer to achieving your health goals.

Take one Gut+ capsule daily with food. Preferably, at breakfast time. This gives your supplement all day to work its magic, saving night hours for (digestive) rest and relaxation. 

If you’re already taking a butyrate supplement, you may want to experiment with timing. Gut+ could be your morning supplement and butyrate may fit better into your lunch or dinner schedule. 

Gut+ and butyrate can be taken together, too. However, if you are taking both supplements, we recommend you start slowly by taking them at separate meal times. This gives your body time to adjust to the new protocol without overwhelm.

I’m Sensitive to Supplements. Should I Expect Any Side Effects? 

We get it. Your gut is already out of whack and you don’t want to make symptoms worse. The good news is, any die-off effects caused by Gut+ are short-lived. And, most people don’t experience side effects at all. If you’re worried, here are some survival tips to help curb any side effects:

  • Make sure you take Gut+ with a full meal.
  • You can take both Gut+ and butyrate daily. But, if you’re sensitive, it’s best to work your way up to taking both at once.
  • If you find that Gut+ is too much for your body to handle right now, try taking butyrate first. Butyrate has a lower dosage per capsule and doesn’t include Preforpro prebiotics. Once you feel comfortable, you can switch over to Gut+.
  • If your heart is set on Gut+, simply lower the dosage and take it once every two days until your body gets used to it. 

Are you experiencing side effects? We’ve found that any side effects (usually mild constipation) resolve themselves after a few days.

Can I Open Gut+ Capsules and Take Them With Food or Water?

Gut+ is carefully formulated for optimal absorption and bioavailability in a one capsule dose. For this reason, we don’t recommend altering the capsules in any way or opening them.

Can I Have a “Die Off” Reaction with Gut+?

Yep, it’s totally possible to have a detox or “die off” reaction when taking Gut+, as it is with any supplement, especially for those who are sensitive. However, it’s unlikely. Flu-like symptoms, headache, or fatigue are typically a sign that you are killing off a pathogen and/or rebalancing the microbiome. When this happens, you may need to support your drainage pathways. 

Here are some ways you can support your body through the detox process: 

  • Liposomal glutathione
  • NAC
  • Milk thistle
  • Dry brushing
  • Infrared sauna use
  • Exercise/movement 
  • Rebounding (trampoline jumping is great for your lymphatic system!)
  • Castor oil packs
  • Liquid minerals for energy
  • Lymphatic massage
  • Support your brain and cell membranes with BodyBio PC

People with a complicated medical history (chemical sensitivity, mold exposure, parasites, Lyme disease, SIBO, glyphosate toxicity, etc.) are generally more likely to experience a Herxheimer reaction when taking Gut+, but it isn’t guaranteed. 

If you feel anxious about beginning Gut+, take a moment to evaluate your drainage pathways. Do you struggle to sweat? Do you poop daily? Do you digest fats correctly? It may be helpful to make some progress on these blockage issues before beginning Gut+. However, Gut+ may also be the catalyst to improving some of these issues by rebalancing your microbiome. This is an individual process, so evaluate your situation and proceed accordingly. 

What are PreforPro Prebiotics?

We believe Preforpro prebiotics are the most scientifically advanced way to gently curb dysbiosis and rebalance your gut. But what are they exactly? Preforpro is a bacteriophage that gently eliminates unwanted bacteria from the gut — leaving room for healthy bacteria to grow and flourish. The bacteriophage prebiotics are designed to support your healthy gut bacteria without causing the bloating and gas that fiber-based prebiotics sometimes do.

Is Gut+ Meant to Replace Butyrate? 

Since Gut+ contains highly absorbable tributyrin, it can be used as a replacement for your everyday butyrate supplement. Think of it as our new state-of-the-art butyrate option. However, Gut+ doesn’t have to replace butyrate if butyrate is working perfectly fine for you now. Some people also find added benefits in taking both supplements daily.

Do I Take Gut+ with Butyrate? 

We recommend you evaluate your gut health status before replacing butyrate with Gut+. If you have a number of digestive complaints, it may be beneficial to take both supplements daily. If symptoms are mild or you are looking to maintain healthy gut status, you can probably get away with Gut+ alone. One way to evaluate your gut health is to take a test like the Thorne Onegevity Gut Test. 

Should I Switch to Gut+ If I Currently Take Butyrate?

If you only have the budget or capacity for one gut supplement, it may be beneficial to switch to Gut+. This is because Gut+ includes Preforpro prebiotics and postbiotics and is unlike any other gut supplement on the market. Essentially, it’s a broader approach to digestive health than taking butyrate alone. 

Everyone reacts differently to supplements, so we recommend you try Gut+ and butyrate for up to 1-3 months each to evaluate the benefits. Then, choose the one that works best for you.

Do I Need to Take a Probiotic Supplement with Gut+?

Broad-spectrum probiotics aren’t as effective as clever marketing wants you to believe. In fact, 66% of BodyBio customers said their probiotic supplement had little to no effect on their overall gut health. Yikes!

Instead of probiotics, Gut+ uses prebiotics and postbiotics to improve gut health. These provide fuel and support for the healthy bacteria that are already growing in your gut — allowing it to prosper naturally. 

No, you don’t necessarily need to take a probiotic supplement in addition to Gut+. If you have a probiotic you really love, by all means, keep taking it. But if your probiotic supplement doesn’t provide any results, it’s time to ditch it and watch Gut+ do its magic.

Can Gut+ Replace My Current Probiotic Supplement?

Your microbiome is as unique as your fingerprint. It’s made up of trillions of microscopic bacteria that can impact your digestion for good or bad. When you take a broad-spectrum probiotic, your body doesn’t necessarily have the fuel (prebiotics and postbiotics) to support it. And, you’re shooting in the dark because you don’t actually know what bacterial strains your body needs. 

We created Gut+ as a probiotic replacement. Its goal is to work alongside your unique microbiome — instead of trying to replace it with unknown probiotics. Prebiotics and postbiotics provide fuel for your natural microbiome to thrive.

Gut+ vs. Butyrate Major Differences

How about a side-by-side comparison of Gut+ versus butyrate? We’ve got you. Here, you can evaluate the differences between these two cutting-edge supplements and decide which one is best for you.

chart of butyrate vs. gut plus differences

Major Gut+ Benefits vs. Butyrate Benefits

In addition to the benefits listed in our chart above, there are a few other things you should know about Gut+ and butyrate for gut health: 

Gut+ is designed as an all-in-one gut health supplement. You no longer have to sort through dozens of pills each morning hoping that one of them will take care of your gut dysbiosis. Preforpro bacteriophage prebiotics and ultra absorbable tributyrin combine for full body benefits like blood sugar regulation, detox, digestion, and brain support. Think of it as a more advanced form of our trusted butyrate supplement. 

Read more: What is Gut+? 

BodyBio Butyrate has been recommended by practitioners for decades. It contains just butyrate and minerals (sodium or calcium and magnesium) for a simple approach to healing gut permeability. It focuses on gut lining integrity, supports a healthy inflammatory response, and supports blood sugar balance.  

Read more: What is Butyrate? 

Sodium vs. Calcium/Magnesium Butyrate

Curious to know more about the benefits of butyrate? We offer two kinds of butyrate supplements: calcium and magnesium butyrate and sodium butyrate. One of our most common questions is: which kind is best for me? Check out this blog post for answers.

We Want to Heal Digestive Distress Worldwide

Gut dysbiosis is no joke — and it’s on the rise. Around 60 to 70 million people suffer from digestive diseases worldwide. One recent US-based study suggests that almost 2 out of 3 people suffer from gut problems.
Our supplements have been trusted by practitioners for decades — and best of all, they’ve helped hundreds of people remember what life was like before gut symptoms. If you’ve tried everything to heal your gut, without any results, then we created Gut+ for you.

I’m Ready to Take Charge of My Gut Health

References

Almario, C. V., Ballal, M. L., Chey, W. D., Nordstrom, C., Khanna, D., & Spiegel, B. M. R. (2018). Burden of Gastrointestinal Symptoms in the United States: Results of a Nationally Representative Survey of Over 71,000 Americans. The American journal of gastroenterology, 113(11), 1701–1710. https://doi.org/10.1038/s41395-018-0256-8


Liu, H., Wang, J., He, T., Becker, S., Zhang, G., Li, D., & Ma, X. (2018). Butyrate: A Double-Edged Sword for Health?. Advances in nutrition (Bethesda, Md.), 9(1), 21–29. https://doi.org/10.1093/advances/nmx009


Żółkiewicz, J., Marzec, A., Ruszczyński, M., & Feleszko, W. (2020). Postbiotics-A Step Beyond Pre- and Probiotics. Nutrients, 12(8), 2189. https://doi.org/10.3390/nu12082189


Slavin J. (2013). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), 1417–1435. https://doi.org/10.3390/nu5041417