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March 08, 2022

7 Legit Hacks to Heal Your Gut and Feel Your Best

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We might be biased, but it seems like in the last few years the integrative medicine obsession with gut health has nearly gone mainstream. Probiotics, juice cleanses, bone broth, and other gut healthy foods, recipes, and supplements are more popular than ever. But are they always the answer to improve gut health naturally? In this article, we’ll break down 7 legit hacks to heal your gut – and they aren’t all about your diet. 

Table of Contents:

The Importance of Gut Health and Your Microbiome

If you’re reading this article right now, odds are pretty good you have at least some idea of just how incredibly important your microbiome and your gut health are for your overall wellbeing. (We know our audience has some of the most curious, health-minded folks around!) But everyone could do with a refresher now and again, so as a reminder, here are some of the many things your gut and microbial community do for you, their gracious host. 

  • Probiotic bacteria digest your food and turn prebiotic fiber into postbiotics, like short-chain fatty acids and vitamins. 
  • A healthy microbiome protects the gut environment from invading pathogens that enter the body on your food and drink. 
  • A healthy microbiome produces neurotransmitters that affect your mood and nervous system operations. 
  • Probiotics protect the gut lining, so that nutrients are absorbed well and waste particles are kept out of the bloodstream. 
  • The gut holds 70% of our immune system.

And this is really just hitting a few highlights on the gut and microbiome. The ecosystem of the gut serves as one of the most interconnected networks to the health of the whole body. 

Signs and Symptoms of an Unhealthy Gut

So when something begins to go awry with our gut health, it isn’t long until digestive symptoms begin to add up, along with mental health challenges, decreased brain function, hormonal imbalances, and more. You might notice: 

  • Bloating, gas, diarrhea, constipation, abdominal discomfort/pain, or any combination of these
  • Food intolerances
  • Fatigue
  • Depression
  • Anxiety
  • Mood swings
  • Irregular menstrual cycles
  • Brain fog
  • Lack of resilience to stress
  • Low energy
  • Low motivation.

An unhealthy gut can truly impact you on a multi-system level. Fortunately, that also means that we can take big steps toward healing by improving our gut health. 

How To Improve Gut Health

Improving gut health begins with a healthy diet. So we’re skipping over that one this time, because we’re betting you already know all about avoiding gluten, eating lots of fruits and vegetables, getting more fiber in your meals, and making sure to get enough protein. Like we said before, you’re not any old Joe Schmoe who eats cardboard box pizza three times a week. 

When you have serious gut issues – or you're just taking your gut health seriously – it can be the extra practices you put in place after your diet is locked in that make the biggest difference. We’re talking stress, sleep, probiotics, antimicrobials, and more. Let’s dig into these seven tips for a healthier gut. 

Eat More Foods With Butyrate

…Or foods that help your probiotics make butyrate in the gut. And ok, this is technically diet-related. But just because you eat a Paleo or Keto diet doesn’t mean you’re automatically getting all the butyrate your gut needs. In fact, it’s highly unlikely that you are. 

Butyrate is a gut-healing short-chain fatty acid produced by certain types of bacteria in the large intestine. It has many wonderful uses, including protecting and nourishing the gut lining (bye bye leaky gut!) and supporting the immune system [1]. 

Our gut bacteria mostly make butyrate in house, but we can get it from certain food sources as well. Dairy products (preferably grass fed) like butter and parmesan cheese contain small amounts of butyrate. 

Of course, dairy is a no go for many of us, so in that case, reach more for butyrate-producing foods like cold, cooked rolled oats, legumes, potatoes, and rice. The cooking and cooling process makes these foods a type of fiber called resistant starch, which butyrate-producing bacteria love to munch on. 

Seriously Lower Stress

Seriously! With work, families, and the many obligations of modern life, taking time to actively slow down our breathing, go for a walk, practice yoga, or sit down for a quiet meditation often gets pushed to the side. 

But the gut is incredibly sensitive to stress, and digestive issues and fatigue are often signs that your body is feeling that stress, even if you aren’t consciously aware of it [2]. Stress management has to take priority if gut healing is going to occur. 

Find ways to disconnect your brain and ground into your body, whether that’s breathwork, exercise, or an enjoyable hobby you love. Life is too short to spend it worrying and ruminating.

Use Probiotics Strategically

Probiotics have been touted as a gut health cure-all for many years now. And we can’t deny that they have earned their place and have the research to back up their usefulness [3, 4]. 

However, the “throw it at the wall and see what sticks” approach often used with probiotics may end up being more harmful down the road for some people, especially critically ill people or those with autoimmune disease ​​[5, 6]. 

If you’re interested in incorporating probiotics into your daily routine, we suggest working with a practitioner who can use clinical evaluation and testing to identify which strains may be most helpful for you. 

Use Antimicrobials With Caution

Antimicrobials – usually herbs with the ability to kill bacteria, fungi, parasites or all of the above – are another popular holistic treatment option for addressing bad microbes that have set up shop in the gut [7]. These medicinal plants and herbs, such as artemis, berberine, and even peppermint, can kill off everything from candida to roundworms when used properly. 

But if you go too hard too fast, you might get a die-off reaction, which is what happens when a whole bunch of bad bacteria or microbes die and release toxins into the gut and then the bloodstream. You might experience a worsening of your current symptoms, or you might feel like you caught the flu. Either way, pushing your body and immune system too hard only makes you more susceptible to the same or different bad bugs taking the place of the ones you just killed off. 

We recommend the same strategy here as with probiotics – find a practitioner who can recommend an antimicrobial regimen specific to your microbiome’s needs. And always listen to your body! If you feel worse on antimicrobials, back off on the dose or stop completely until you feel like you can handle them again. 

Rub Some Dirt on It 

Getting your hands (and feet) outside in the dirt can actually help your microbiome become more diverse and resilient [8]. Gardening, playing around the yard with the dog or the kids, mud wrestling – it’s all fair game for boosting your microbial army. 

We have tons of research showing that spending time in nature is extremely stress-relieving, too, so planting some flowers in your backyard is like a two-for-one gut therapy [9, 10]. 

Sleep Like It’s Your Job

Ah, sleep. For many of us, it’s a daily challenge – trouble falling asleep, staying asleep, and getting enough hours are all-too-common issues. But maybe that’s because we’re approaching sleep wrong, or we’re not really making a commitment to our sleep. We love a good Netflix drama as much as the next person, but when watching right before bed keeps your mind racing as you toss and turn, is it really worth it? 

And yes, less sleep or disrupted sleep = an unhappy gut. A 2020 study on sleep, circadian rhythm, and the microbiome states that sleep fragmentation and short sleep duration are associated with gut dysbiosis [11]. 

Here are just a few sleep hygiene tips: 

  • Keep your home lighting low at night, preferably from table lamps or candles (not overhead lighting).
  • Create a bedtime routine at least one hour before lights out – this trains your body to release stress from the day and prepare for sleep.
  • Use earplugs, blackout curtains, and/or a sleep mask to block out stimuli that might cause you to wake up during the night. 

Fasting Isn’t Always Right for Everyone

Probably not the fasting advice you were expecting, right? Fasting, whether intermittent fasting or longer term fasting, has become a popular strategy to give the gut a rest from digesting food. The idea is that, when it doesn’t have to mobilize the digestive process, fasting allows the gut to perform cellular housekeeping and heal inflamed tissues. 

For many people, this is a perfectly sound strategy. But we have to caution that not everyone does well with fasting, especially when they are already low on essential nutrients or have active disease, such as IBD patients. Women should also be careful with any kind of fasting, since it can disrupt hormones and increase cortisol (stress hormone) [12, 13]. 

Sometimes, the gut actually needs a higher nutrient intake to heal, rather than deprivation. Focusing on vitamin and mineral-dense yet easy-to-digest foods like smoothies, soups, well-cooked vegetables and fruits, and low and slow-cooked meats may be more healing to the gut and the body overall. 

Restore Your Gut Health Today

Healing the gut takes a multi-pronged approach, incorporating restful deep sleep, stress relief, healing foods, and sometimes strategic supplements like probiotics, antimicrobials and butyrate. It also takes time, patience, and being kind to yourself as you make progress and mistakes along the way. But it is possible! You have the power to change your lifestyle to one that supports your gut health and your overall wellbeing.  

Check out the gut healing power of BodyBio Butyrate here.

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Ashley Palmer | 10.27.2026

Semaglutide Can Change What People Want to Eat. Here's What Your Gut Has to Do With It.

Imagine you order the meal you've loved for a decade, and a few bites in, you realize you just don't care about it. You're not full, exactly. Just uninterested.

Many people taking semaglutide (a GLP-1 medication) describe this experience. Foods that were reliable favorites suddenly seem greasy, or too sweet, or just vaguely off. Scientific American captured the strangeness: a former food writer losing interest in cooking, longtime favorites tasting wrong.

The obvious explanation is that these medications make you feel full sooner. But fullness doesn't explain why a specific curry tastes bitter now, or why a go-to wine suddenly tastes off. Something more is happening, and it points to a hormone your body has been producing your whole life.

In this article, we'll look at what the newest research suggests semaglutide does to food preferences, what GLP-1 actually does inside the body, and where your gut microbiome and a short-chain fatty acid called butyrate fit into that system.

Table of Contents:

  • Semaglutide Isn't Only Changing How Much People Eat
  • Your Gut Was Making GLP-1 Long Before Ozempic
  • Where the Microbiome Comes In
  • Can Butyrate Support Natural GLP-1 Production?
  • Why Butyrate Matters Beyond One Hormone
  • Support the System, Not Just the Signal
  • The Bigger Story Your Gut Was Already Telling

Semaglutide Isn't Only Changing How Much People Eat

Researchers are starting to document what users have been describing anecdotally.

A 2026 observational study of hospitalized Japanese patients with type 2 diabetes found that those on semaglutide showed significantly reduced preference for sweet carbohydrates, non-sweet carbohydrates, and non-sweet fats — while preferences for protein and dietary fiber stayed essentially unchanged. This wasn't a blanket loss of interest in food. It was a selective shift.

For someone focused on weight loss, eating less may be the point. Still, a reduced appetite for fats is worth paying attention to, since dietary fats supply essential fatty acids and help the body absorb fat-soluble vitamins.

Taste perception may also contribute. In a 16-week, randomized, placebo-controlled study of 30 women with obesity and PCOS, semaglutide improved overall taste recognition scores and altered brain activity in response to both food images and a sweet solution. In other words, participants' sense of taste sharpened, which may help explain why some foods suddenly seem too strong.

A 2025 study found the opposite: reduced sensitivity across all five basic tastes in people taking GLP-1 medications compared with matched non-users. That means the more accurate takeaway isn't "Ozempic makes food taste different" so much as "GLP-1 signaling reaches further into how we experience food than many researchers expected."

None of these studies settles the question on its own. But together they point somewhere useful: GLP-1 isn't only a satiety signal. It appears to play a role in how appealing food seems in the first place.

Your Gut Was Making GLP-1 Long Before Ozempic

Here's what often gets lost: GLP-1 wasn't invented by a pharmaceutical company.

GLP-1 is a hormone your intestines release on their own, produced mainly by specialized cells called enteroendocrine L-cells. These cells sit in the gut lining, acting as sensors that detect what's arriving from your meal and releasing hormones that coordinate the response.

GLP-1 helps regulate insulin release, slows how quickly the stomach empties, contributes to satiety, and carries information from the gut to the brain. GLP-1 medications didn't create a new pathway. They target one your body was already running.

But there's an important difference, and a lot of wellness marketing glosses over it. Your body's own GLP-1 is broken down within minutes of release. Semaglutide is engineered to resist that breakdown and activate GLP-1 receptors far more strongly, for far longer.

Supporting your body's own GLP-1 signaling through food or the microbiome isn't a lesser version of taking semaglutide. It's a different thing entirely.

Where the Microbiome Comes In

Your gut bacteria eat what you don't digest.

When fermentable fibers and resistant starch reach the colon, bacteria ferment them and produce short-chain fatty acids (SCFAs), mainly acetate, propionate, and butyrate. These aren't waste products. They're signaling molecules, and the cells lining your intestines are built to receive them.

Intestinal cells carry receptors, including FFAR2 (also called GPR43) and FFAR3, that detect short-chain fatty acids. When SCFAs bind these receptors on L-cells, they trigger an internal cascade that can influence the release of gut hormones, including GLP-1 and a related satiety hormone called PYY.

So the pathway is real: fiber arrives, microbes ferment it, metabolites are produced, gut cells sense them, hormones get released, and the gut communicates with the pancreas and the brain. That last link is worth sitting with — your gut and brain are in constant conversation, and food-derived microbial metabolites are part of what they're saying to each other.

The quick version of this compresses to: fiber → butyrate → GLP-1 → less hunger. The actual biology is an ecosystem with many signals, of which butyrate is one.

Can Butyrate Support Natural GLP-1 Production?

The mechanistic evidence is strong. The human evidence is thinner, but still developing.

A small 2026 study in adults with obesity found that oral sodium butyrate combined with L-arginine significantly increased circulating GLP-1. That's encouraging, but the study had only seven participants, butyrate wasn't tested on its own, and participants reported no difference in hunger or fullness.

By contrast, in a 2025 randomized controlled trial of 50 adults with obesity, people taking sodium butyrate alongside a reduced-calorie diet saw reductions in weight, BMI, and waist circumference, but their serum GLP-1 didn't change significantly.

A 2026 randomized, double-blind trial of 46 adults added more nuance. After 12 weeks of sodium butyrate plus a moderately reduced-calorie diet, participants with obesity lost a meaningful amount of weight. Participants who also had type 2 diabetes did not, although their blood sugar control improved.

That pattern echoes an earlier finding. In a 2018 study, four weeks of oral butyrate improved insulin sensitivity in lean men but not in men with metabolic syndrome.

Together, these suggest butyrate's effects depend heavily on metabolic context: who you are, what your microbiome looks like, and where the butyrate ends up. But GLP-1 is only part of the story.

Why Butyrate Matters Beyond One Hormone

Focusing only on GLP-1 undersells what butyrate does.

Butyrate is the primary fuel source for colonocytes, the cells lining your colon. Not a supporting nutrient. Their main energy supply. Those cells use butyrate to power the work of maintaining a functioning gut lining, the barrier that decides what passes from your digestive tract into your body and what doesn't.

This is where the cellular health picture comes together. A well-fueled intestinal lining supports a healthy gut barrier. A healthy barrier supports a stable environment for the microbial community living there. And that community produces metabolites that signal to the rest of the body — including the gut-to-brain communication involved in appetite and satiety.

Butyrate sits at the center of that loop as both fuel and message. That role holds regardless of what the GLP-1 research eventually concludes.

Support the System, Not Just the Signal

The takeaway isn't that you should be trying to maximize GLP-1. Your metabolism and gut function are more complex than one signal.

Lasting metabolic regulation runs on an ecosystem: microbial diversity, adequate fermentable fiber, well-nourished intestinal cells, an intact gut barrier, and steady communication between gut and brain. Semaglutide shows what happens when you push one signal in that system very hard. It doesn't show that one signal is the whole system, or the only way to modulate it.

Feeding that ecosystem starts with fiber-rich whole foods: vegetables, legumes, cooked-and-cooled potatoes and rice (good sources of resistant starch), and other plant foods your gut bacteria can thrive on. Give it time. Gut environments shift over weeks and months, not days.

For targeted support, BodyBio Butyrate provides butyrate in supplement form to support the gut lining and a healthy microbiome.*

The Bigger Story Your Gut Was Already Telling

Semaglutide has taught researchers a great deal about how strongly GLP-1 signaling can influence not just hunger but desires: what sounds good, what tastes right, and what gets left on the plate.

And yet, the more interesting revelation may be how much was already happening without it. Every meal you eat feeds a microbial community that turns fiber into signaling molecules, which intestinal cells read and translate into messages sent onward to your pancreas and your brain. That conversation has been running your entire life.

Butyrate is one voice in that conversation. It fuels the cells that hold your gut barrier together and takes part in the signaling between your microbiome and the rest of your body. Supporting butyrate production in the gut won't replicate a pharmaceutical. It doesn't need to. Feeding the system well is its own goal, and the benefits build gradually, often in small shifts that are easy to miss at first.

Support your gut at the cellular level with BodyBio Butyrate.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

This article is for educational purposes only and is not a substitute for medical advice. If you're taking semaglutide or another GLP-1 medication, talk with your healthcare provider before adding new supplements.

Ashley Palmer | 06.16.2026

Comprehensive Guide to Butyrate: What it is, Benefits, Side Effects, & More

Butyrate is a necessary component to a balanced microbiome, also working as an inflammation guard*. One of several, short-chain fatty acids created from fermented resistant starches, low butyrate levels have been associated with serious health concerns.

Ashley Palmer | 04.24.2026

Butyrate and IBS: What Your Gut Cells Actually Need

You've tried the probiotics. You've cleaned up your diet. You're doing everything you're supposed to do, and your gut still isn't cooperating.

If you have IBS, that frustration is familiar. Bloating, urgency, unpredictable mornings, the constant guessing game of what's going to set things off.

What often gets missed in the conversation around IBS isn't a trendy new supplement or a stricter elimination diet. It's something more foundational: what your gut's own cells actually need to function.

Here's a closer look at what butyrate does, why IBS and low butyrate levels are closely linked, and how supporting the gut at the cellular level can make a difference.

Table of Contents:

  • Understanding Butyrate

  • How Butyrate Works in the Gut

  • Why This Becomes an Issue for People With IBS

  • Supporting the Body More Effectively

  • Butyrate, IBS, and the Cellular Health Connection

  • How Butyrate Supports IBS Comfort Long-Term

Understanding Butyrate

Butyrate is a short-chain fatty acid (SCFA) produced in the colon when beneficial gut bacteria ferment dietary fiber, specifically resistant starch. It belongs to a class of compounds called postbiotics, the functional byproducts of a healthy microbiome.

Unlike probiotics, which are living bacteria, butyrate is a metabolite. It's a compound your body puts to work directly at the cellular level. Understanding the difference between probiotics and postbiotics, like butyrate, is a useful shift you can make when thinking about gut health.

Why the Body Relies on Butyrate

Your colon is lined with specialized cells called colonocytes. These cells run almost entirely on butyrate, providing up to 90% of their energy needs.

When colonocytes have what they need, they do their job well. They maintain the integrity of the gut lining, regulate what passes into the bloodstream, support a healthy inflammatory response, and help keep gut motility on track. Without enough butyrate, the gut’s main source of energy, the gut simply can't do its job well.

How Butyrate Works in the Gut

Butyrate supports three interconnected systems in the gut: the gut lining, the immune environment, and gut motility.

The gut lining is just one cell layer thick. Butyrate fuels those cells and supports the tight junctions between them, the structural connections that keep the barrier intact and functioning.

At the immune level, butyrate helps the body maintain a balanced inflammatory response in the colon without triggering overactivation. And because it directly influences the rhythmic contractions that move contents through the digestive tract, it plays a meaningful role in the irregular patterns that so many people with IBS experience.

What Happens When Butyrate Levels Are Supported vs. Strained

When butyrate is available in adequate amounts, the gut lining stays resilient, motility is more regular, and digestive comfort improves, whether you have a diagnosis of IBS or not.

If butyrate levels fall short, the gut barrier may become less stable, motility can become unpredictable, and the colon's immune environment may shift. How pronounced these patterns are varies from person to person. Diet, stress, genetics, and microbiome composition all play a role in your body’s patterns too.

Why This Becomes an Issue for People With IBS

Modern Stressors on Butyrate Production

Butyrate is made by gut bacteria that ferment resistant starch, a type of fiber found in foods like cooked and cooled potatoes, legumes, and underripe bananas. The modern diet is low in these foods. That means many people simply aren't giving their gut bacteria the raw materials they need to produce adequate butyrate levels.

Antibiotic use, chronic stress, and certain medications can also reduce the population of butyrate-producing bacteria in the colon. Over time, that compounds the butyrate production gap.

Why Common Approaches Often Fall Short

Probiotics can be a valuable part of gut health support, but most probiotic strains are not butyrate-producing species. They can shift the microbiome, but they don't directly address the fuel shortage that many IBS-related symptoms may stem from.

Fiber-based approaches come with a similar challenge. In some people with IBS, increasing fermentable fiber can worsen bloating and gas before it helps, because a disrupted microbiome may not efficiently use that fiber to make butyrate.

Since butyrate works at the cellular level, the signs of low butyrate can overlap common IBS symptoms, which is part of why the connection between the two gets overlooked.

Supporting the Body More Effectively

Foundational Support for Butyrate Production

Diet is the first step to improving the body's natural butyrate production. Foods high in resistant starch give butyrate-producing bacteria what they need to function properly.

Foods that naturally support butyrate production include cooked and cooled rice, potatoes, and legumes. A steady intake of resistant starch over time does more for the microbiome than occasional high-fiber days followed by low-fiber ones.

Stress management and adequate sleep can also support a more stable gut environment. Chronic stress directly affects microbiome composition and motility through the gut-brain axis. 

When Targeted Butyrate Support Makes Sense

For people whose microbiome is disrupted or whose diet can't consistently provide enough resistant starch, direct butyrate supplementation is another option for long-term support.*

Supplemental butyrate delivers the short-chain fatty acid directly to the colon, where colonocytes can put it to use.* Clinical research has shown that sodium butyrate supplementation is associated with improvements in abdominal comfort and bowel regularity in people with IBS.

Sodium butyrate and calcium magnesium butyrate are both effective options, and the differences between which works best for your body often come down to your individual health history and mineral needs.*

Butyrate, IBS, and the Cellular Health Connection

IBS is complex, and its causes vary from person to person. But one consistent finding in the research is that people with IBS tend to have lower levels of butyrate-producing bacteria and overall reduced short-chain fatty acids in the gut. That points to a cellular resource problem as much as a microbiome problem.

When the cells lining the colon are undersupported, the entire digestive environment becomes less stable. Gut barrier function, motility, immune signaling, and communication along the gut-brain axis all depend on colonocytes having what they need to function.

Supporting the gut at the cellular level is not a replacement for other gut health practices (whole food probiotics, exercise, etc.). It’s the foundation that makes those practices more effective. When your cells are supported, the body functions more efficiently as a whole.

How Butyrate Supports IBS Comfort Long-Term

IBS can feel like a moving target, and the path toward better digestive comfort is rarely a straight line or a quick fix. Supporting your gut at the cellular level creates a more stable foundation, and that starts with making sure colonocytes have the fuel they need.*

Butyrate works best as part of a consistent approach that includes diet, lifestyle, and targeted support where needed. Progress tends to be gradual, and that's expected. It reflects the time it takes for the gut lining to strengthen and the microbiome to rebalance.

IBS makes a lot more sense when you know what the gut's cells actually need. And that clarity is often where real progress begins.

Support your gut at the cellular level with BodyBio Butyrate.*